Master STAPS - Engineering and physical activity ergonomics # Course: Bioengineering of tissues and implants

In the BTI master's degree, medical devices have the particular aim of developing, optimizing or evaluating artificial organs, replacement biomaterials with the ultimate aim of improving the service provided to the patient through better functionality, improved longevity and a reduction in side effects raise questions relating to clinical, scientific or industrial issues.

The acquisition of knowledge on medical devices, on host tissues and now on the entire tissue engineering strategy is essential. It is for this purpose that work is developed on themes in cellular, tissue and organic biomechanics. This work focuses on the development of new models, new methods and approaches to better describe, understand and therefore apprehend the functioning and dysfunction of biological systems. The objective of these approaches is to optimize and innovate in the prevention, diagnosis and therapy of these dysfunctions. They also aim to better take into account major public health problems such as bone fragility linked to aging (osteoporosis), the deposition of atheroma plaques in the vessels, or the remodeling of bone in contact with implanted prostheses.

The BTI course trains students on the entire life cycle of a medical device, from concept to design to marketing, with awareness of standardization and regulatory issues. Whether they are clinicians or scientists, the students are able to intervene in different phases of the implantation of an EMR: pre-operative planning, with for example the design of EMRs or personalized ancillaries; post-operatively for the evaluation of the results using modeling or motion analysis tools.

E-candidate : https://candidatures.univ-amu.fr/candidatures/# !homeView

Entry into the Bioengineering of Tissues and Implants master can be done in M1 as in M2.

In M1, the master is aimed primarily at students from scientific fields who have validated a license in the field of Science, Technology and Health with mentions for example STAPS, Life Sciences, or Mechanics, Engineering...

In M2, the Bioengineering of Tissues and Implants master is aimed at students who have validated the M1 BTI, or fifth-year students from an engineering school with which the training is a partner, students from medical or other M1 in the field of Science, Technology and Health.

Admission, whether in the 1st or 2nd year of a master's degree, is based on a recruitment process according to the methods voted by the establishment's authorities.

Students from scientific backgrounds who have completed a Bachelor's degree in the field of Science, Technology and Health.

Entry into working life can also be done by completing a thesis, in France or abroad, which the significant backing of research training favors. The doctoral student's salary, a real three-year fixed-term contract, can then be provided, for example, by academic doctoral allowances or CIFRE contracts involving a company. Doctors can then pursue their career either in the public sector (University, large research organizations) or within the R&D department of companies as a manager or research engineer.

Concretely, this research aims to provide assistance to the clinician both at the level of the surgical gesture and in the improvement of the materials commonly used in his medical practice. Finally, this work is oriented towards patient comfort by validating, for example, minimally invasive percutaneous techniques.

The training aims to provide clinicians with the general knowledge allowing them to have a global understanding of the problems dealt with, the methods implemented by the engineers and the industrial solutions and problems.

Clinically, students must have knowledge of anatomy, biology, clinical imaging or surgical techniques. On the scientific level, these skills must be multidisciplinary, multiphysical and multiscale. It is a question of training them in a scientific approach by giving them the ability to carry out bibliographical studies, to develop critical analyzes of both their own work and that of the literature, to be able to appropriate the objectives of the missions entrusted to them, to discuss and adapt them if necessary, to put in place the appropriate methodologies, to process the results and to discuss them. Students must know biomaterials, the techniques that allow them to be analyzed and characterized. They must be trained in modeling the mechanical behavior of the materials studied and be trained in the use of associated tools.

During the course, the skills acquired are in particular:

Knowledge :

Knowledge of mechanics of solid and fluid continuums
Knowledge of anatomy, biology and surgical techniques
Knowledge of biomechanics of the osteoarticular system
Knowledge of (bio)materials, their properties, their manufacturing methods, and their uses
Knowledge in mechanobiology, tissue engineering.

The skills:

Mastery of the analysis of images from digital imaging – 3D reconstruction (Mimics)
Mastery of digital CAD tools, Finite elements, Optimization
Mastery of the mechanics of EMDs, their design and the reasons for their failures
Mastery of test devices in mechanics and biology

Mastery of standardization and regulatory affairs processes

The practical internship will last 6 months, i.e. approximately 480 hours. The work carried out during this internship will be reported in a dissertation and presented during an oral defense before the specialty jury. This internship may take place in a research laboratory, the R&D department of a company or other services such as, for example, the regulatory affairs department of a company.